Does ACh (Nicotinic Receptors) activate a second messenger system inside the cell?
what are the target cells it acts on?
- RolandLv 77 years agoFavorite Answer
Acetylcholiine is a neurotransmitter,
and neurotransmitters do not activate 2nd messengers inside a cell.
Neurotransmitters open ion channels (Na+ channels, for example).
Many hormones, reaching a cell from the bloodstream, activate 2nd messengers,
but not neurotransmitters.
Also, it's not strictly accurate to refer to neurotransmitters as having "target cells".
The cells that a neurotransmitter interacts with are right on the other side of a synapse,
so if one knows where the synapse is, then there is no question about which cell the
transmitter will interact with.
Hormones have target cells - being in the blood, they come in contact with
all the other cells in the body, but only interact with specific ones - their target cells!
- 5 years ago
No Dear Nicotinic receptors doesnt activate the second messenger, beacuse the nicotince receptors are ligand gated ion channels, the receptors for nicotine are present on specific area in the body, NM Junction, Autonomic ganglia, Adrenal medulla..