Emi asked in Science & MathematicsBiology · 4 weeks ago

How to solve this genetics exercise?

In a population in balance people with MN genotype are 3 times more than those with group NN. Find frequency p(LM) and q(LN)

1 Answer

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  • 4 weeks ago

    Let frequency of NN = x, and frequency of MN = 3x. 

    From the Hardy-Weinberg equation,

    x = q^2 and

    3x = 2pq

    Also, you know that p = 1-q, so 3q^2 = 2(1-q)q

    Factoring out q gives: 3q = 2-2q

    5q = 2

    q = 0.4

    p = 1-q = 0.6

    So, the frequency of LM (p) = 0.6 and frequency of LN(q) = 0.4

    This all works since q^2 = 0.16 and 2pq = 2(0.6)(0.4) = 0.48 = 3x.

    There may well be a different way to get to this answer, but this is how I saw it.

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